P44/42 MAPK (ERK1/2) 單克隆抗體
| 貨號 | 品牌 | CAS | 規(guī)格 | 銷售價(RMB) | 折扣價(RMB) | 備注 | 數(shù)量 |
| ABM0071-100μL | Abbkine | 無 | 100μL | 1998 | 1998 | 無 |
商品信息
| 產(chǎn)品英文名稱 | P44/42 MAPK (ERK1/2) Monoclonal Antibody |
| 免疫原 | 合成多肽 |
| 宿主 | 小鼠 |
| 反應(yīng)性 | 人, 大鼠, 小鼠 |
| 應(yīng)用 | IHC-P, WB |
| 實驗建議 | 最佳的工作稀釋比例需要客戶摸索優(yōu)化。建議的起始嘗試的稀釋比為：WB：1:1000-1:2000，IHC-P：1:50-1:100。 |
| 克隆性 | 單克隆 |
| 純化工藝 | 使用表位特異性的免疫原，通過親和層析，從小鼠腹水中親和純化抗體。 |
商品屬性
| 產(chǎn)品形式 | 液體溶液 |
| 濃度 | 1 mg/ml |
| 分子量 | 44, 42 KD |
| 儲存緩沖液 | PBS緩沖液（pH 7.4），含有0.5%BSA（穩(wěn)定劑），0.02％疊氮化鈉（防腐劑）和50％甘油。 |
| 保存建議 | 自發(fā)貨之日起，-20°C可穩(wěn)定保存1年。為最大限度的避免損失，請在打開管蓋之前融化抗體并離心。我們建議使用前分裝以避免反復凍融。 |
| 運輸條件 | 藍冰運輸 |
| 警告 | 本文列出的產(chǎn)品僅供研究使用，不適用于人類或臨床診斷。我們產(chǎn)品所推薦應(yīng)用，不是建議使用我們的產(chǎn)品去違反任何專利或許可證。對于使用本產(chǎn)品可能發(fā)生的專利侵權(quán)或其他違規(guī)行為，我們不承擔任何責任。 |
附加信息
| 背景 | MAPK1 (mitogen-activated protein kinase 1) encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs， act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for MAPK1. |
| 基因ID | 5594/5595 |
| 別名 | MAPK3; ERK1; PRKM3; Mitogen-activated protein kinase 3; MAP kinase 3; MAPK 3; ERT2; Extracellular signal-regulated kinase 1; ERK-1; Insulin-stimulated MAP2 kinase; MAP kinase isoform p44; p44-MAPK; Microtubule-associated protein 2 kinase; p |
| 蛋白質(zhì)ID | P27361/P28482 |
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